The Obô Natural Park of São Tomé is a natural park of São Tomé and Príncipe, covering 195 km² of the island of São Tomé. It was established in 2006. It has not yet been assigned to a IUCN protected area category. It covers parts of the districts of Caué, Lemba, Lobata and Mé-Zóchi.
Though the island nation has more than 50 watercourses, water pollution remains a significant problem. A lack of adequate water treatment systems means that the water quality in Sao Tome and Principe is questionable.